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Article

Absence of Smad3 induces neutrophil migration after cutaneous irradiation: possible contribution to subsequent radioprotection.

The American journal of pathology - 1 Jul 2008

Flanders Kathleen C, Ho Benjamin M, Arany Praveen R, Stuelten Christina, Mamura Mizuko, Paterniti Miya Okada, Sowers Anastasia, Mitchell James B, Roberts Anita B

Abstract excerpt

Our previous work showed that 6 weeks after cutaneous irradiation, mice null (knockout, KO) for Smad3, a cytoplasmic downstream mediator of transforming growth factor-beta, demonstrate less epidermal acanthosis and dermal inflammation than wild-type (WT) Smad3 mice. Analysis of the kinetics of in...

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Identifiers

PMID: 18502822
DOI: 10.2353/ajpath.2008.070937
PMCID: PMC2438286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18502822-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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