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Article

Polymer of methyl malonic acid suppress inflammation by downregulating IL-2 through ROS overproduction

2026-01-12

Abstract excerpt

Metabolites belonging to the propionate metabolism pathway can regulate immune cell responses in the context of autoimmunity and chronic inflammation. Methyl malonic acid (MMA), a metabolite in this pathway is known to cause dysregulation of T cell oxidative phosphorylation (OXPHOS) and downregulating pro inflammatory T cell effector functions. However, the effects of MMA on T cell signaling and T cell activation...

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Literature Corpus work
2bc30a2f-f1fc-5554-a5a3-06bffa595ace
DOI
10.64898/2026.01.11.698915
Open publication

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Polymer of methyl malonic acid suppress inflammation by downregulating IL-2 through ROS overproductionDOI 10.64898/2026.01.11.698915
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