Article

Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway

2023-01-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Advanced glycation end products (AGEs) are heterogeneous proinflammatory molecules produced by a non-enzymatic glycation reaction between reducing sugars (and their metabolites) and biomolecules with amino groups, such as proteins. Although increases in and the accumulation of AGEs have been implicated in the onset and exacerbation of lifestyle- or age-related d...

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Literature Corpus work: caca9af1-bb85-5f9e-86b7-8fd60cfb4874
DOI: 10.21203/rs.3.rs-2506588/v1

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