Article

Cell-free Tumor Methylome Analysis of Small Cell Lung Cancer Patients Identifies Subgroups with Prognostic Associations

2022-05-13

Abstract excerpt

<h4>Introduction</h4> Small cell lung cancer (SCLC) is a highly aggressive type of cancer with a high risk of recurrence. The SCLC methylome may yield biologic insight but is understudied due to difficulty in acquiring primary patient tissue. Here, we comprehensively profile the SCLC methylome using cell-free methylated DNA immunoprecipitation sequencing (cfMeDIP-seq). <h4>Methods</h4> cfDNA was extracted from p...

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Literature Corpus work: 2bc2ce2b-24fb-559f-af87-3fcddb911d04
DOI: 10.1101/2022.05.12.491321

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