Article

Genomic alterations and transcriptional phenotypes in circulating tumor DNA and matched metastatic tumor

2024-06-03

Abstract excerpt

<h4> <h4>Background: </h4> </h4> Profiling circulating cell-free DNA (cfDNA) has become a fundamental practice in cancer medicine, but the effectiveness of cfDNA at elucidating tumor-derived molecular features has not been systematically compared to standard single-lesion tumor biopsies in prospective cohorts of patients. The use of plasma instead of tissue to guide therapy is particularly attractive for patient...

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Literature Corpus work: e5c9bc27-4603-5c04-96ad-58c3d9ff0290
DOI: 10.1101/2024.06.02.597054

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