Article

Unveiling targeted cell-free DNA methylation regions through paired methylome analysis of tumor and normal tissues

2023-06-29

Abstract excerpt

<h4>ABSTRACT</h4> Liquid biopsy analysis of cell-free DNA (cfDNA) has revolutionized cancer research by enabling non-invasive assessment of tumor-derived genetic and epigenetic changes. In this study, we conducted a comprehensive paired-sample differential methylation analysis (psDMR) on reprocessed methylation data from two large datasets, CPTAC and TCGA, to identify and validate differentially methylated region...

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Literature Corpus work: bfb08c2c-d5e9-5a70-a607-c1f544c3b75e
DOI: 10.1101/2023.06.27.546654

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