Article

Integrative multi-omic sequencing reveals the MMTV-Myc mouse model mimics human breast cancer heterogeneity

2023-03-29

Abstract excerpt

<h4>Background</h4> Breast cancer is a complex and heterogeneous disease with distinct subtypes and molecular profiles corresponding to different clinical outcomes. Mouse models of breast cancer are widely used, but their relevance in capturing the heterogeneity of human disease is unclear. Previous studies have shown the heterogeneity at the gene expression level for the MMTV-Myc model, but have only speculated...

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Literature Corpus work: 2ba714f6-8128-52eb-8193-0858ba10deaa
DOI: 10.1101/2023.03.28.534611

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