Article

Integrated sequence and gene expression analysis of mouse models of breast cancer reveals critical events with human parallels

2018-07-24

Abstract excerpt

Mouse models have an essential role in cancer research, yet little is known about how various models resemble human cancer at a genomic level. However, the shared genomic alterations in each model and corresponding human cancer are critical for translating findings in mice to the clinic. We have completed whole genome sequencing and transcriptome profiling of two widely used mouse models of breast cancer, MMTV-Neu...

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Literature Corpus work: 92200b8c-52b4-5e61-a260-55558864195b
DOI: 10.1101/375154

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