Article

Polygenic risk score analysis reveals shared genetic burden between epilepsy and psychiatric comorbidities

2023-07-05

Abstract excerpt

<h4>Background</h4> One in three people with epilepsy experiences psychiatric comorbidity, with higher rates in people with drug-resistant epilepsy. Despite their high heritabilities, finding genetic links between epilepsy and psychiatric disorders has proven difficult. We used polygenic risk scoring (PRS) to test whether people with epilepsy have an increased polygenic burden of common genetic variants for depres...

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Literature Corpus work: 2b99f2f0-9670-5030-8ffb-1a88c87eb19c
DOI: 10.1101/2023.07.04.23292071

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