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Article

Heritability and polygenic load for comorbid anxiety and depression

26 Mar 2025

Abstract excerpt

Abstract Anxiety and depression commonly occur together resulting in worse health outcomes than when they occur in isolation. We aimed to determine whether the genetic liability for comorbid anxiety and depression was greater than when anxiety or depression occurred alone. Data from 12,792 genotyped twins (ages 38–85) were analysed, including 1,986 complete monozygotic and 1,594 complete dizygotic pairs. Outcomes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 40140358
DOI: 10.1038/s41398-025-03325-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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