Article
Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders.
Brain : a journal of neurology - 1 Aug 2023
Karadag Naz, Shadrin Alexey A, O'Connell Kevin S, Hindley Guy F L, Rahman Zillur, Parker Nadine, Bahrami Shahram, Fominykh Vera, Cheng Weiqiu, Holen Børge, Alvestad Silje, Taubøll Erik, Steen Nils Eiel, Djurovic Srdjan, Dale Anders M, Frei Oleksandr, Andreassen Ole A, Smeland Olav B
Abstract excerpt
Psychiatric disorders and common epilepsies are heritable disorders with a high comorbidity and overlapping symptoms. However, the causative mechanisms underlying this relationship are poorly understood. Here we aimed to identify overlapping genetic loci between epilepsy and psychiatric disorders to gain a better understanding of their comorbidity and shared clinical features. We analysed genome-wide association...
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