Article

Polygenic risk of psychiatric disorders exhibits cross-trait associations in electronic health record data

2019-11-29

Abstract excerpt

<h4>Objective</h4> Prediction of disease risk is a key component of precision medicine. Common, complex traits such as psychiatric disorders have a complex polygenic architecture making the identification of a single risk predictor difficult. Polygenic risk scores (PRS) denoting the sum of an individual’s genetic liability for a disorder are a promising biomarker for psychiatric disorders, but require evaluation...

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Literature Corpus work: d0e9a611-da05-5353-98a0-9ce5e378c1c8
DOI: 10.1101/858027

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