Article

Engineering stringent genetic biocontainment of yeast with a protein stability switch

2022-11-24

Abstract excerpt

Synthetic biology holds immense promise to tackle key problems we are facing, for instance in resource use, environmental health, and human health care. However, comprehensive safety measures are needed to deploy genetically engineered microorganisms in open-environment applications. Here, we describe a genetic biocontainment system based on conditional stability of essential proteins. We used a yeast-adapted dest...

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Literature Corpus work: 2b8b26a9-5b38-587b-995e-c28b6e83a3aa
DOI: 10.1101/2022.11.24.517818

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