Article

Multiplex <i>in situ</i> hybridization within a single transcript: RNAscope reveals dystrophin mRNA dynamics

2019-10-03

Abstract excerpt

Dystrophin plays a vital role in maintaining muscle health, yet low mRNA expression, lengthy transcription time and the limitations of traditional in-situ hybridization (ISH) methodologies mean that the dynamics of dystrophin transcription remain poorly understood. RNAscope is highly sensitive ISH method that can be multiplexed, allowing detection of individual transcripts at sub-cellular resolution, with differe...

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Literature Corpus work: 2b230446-4c49-5f68-a45c-2865fc115b68
DOI: 10.1101/791780

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