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Super-resolution microscopy of mitochondrial mRNAs

2025-01-24

Abstract excerpt

Mitochondria contain their own DNA (mtDNA) and a dedicated gene expression machinery. As the mitochondrial dimensions are close to the diffraction limit of classical light microscopy, the spatial distribution of mitochondrial proteins and in particular of mitochondrial mRNAs remains underexplored. Here, we establish single-molecule fluorescence in situ hybridization (smFISH) combined with STED and MINFLUX super-re...

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Identifiers and source

Literature Corpus work
21489682-097a-523e-8505-f368d0a3728e
DOI
10.1101/2025.01.23.634455
Open publication

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Super-resolution microscopy of mitochondrial mRNAsDOI 10.1101/2025.01.23.634455
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