Article

Dual Probe Ligation In Situ Hybridization with Rolling-Circle Amplification for High-Plex Spatial Transcriptomics

2025-01-24

Abstract excerpt

<h4>ABSTRACT</h4> New biological insights are increasingly dependent upon a deeper understanding of tissue architectures. Critical to such studies are spatial transcriptomics technologies, especially those amenable to analysis of the most widely available human tissue type, formalin-fixed and paraffin-embedded (FFPE) clinical specimens. Here we build on our previous oligonucleotide probe ligation-based approach t...

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Literature Corpus work: 9204ac72-47d9-55f5-886a-d2f7441a2397
DOI: 10.1101/2025.01.22.634417

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