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Clamp the LAMP: a photoelectrochemical platform for <i>KRAS</i> mutation detection via wild-type blocking

2026-02-22

Abstract excerpt

KRAS mutations are among the most prevalent oncogenic alterations in colorectal, lung, and pancreatic cancer, yet their detection remains analytically challenging in the presence of an overwhelming wild-type (WT) background. Here, we report a photoelectrochemical (PEC) genotyping platform that integrates clamp-inhibited loop-mediated isothermal amplification (C-LAMP) with enzyme-free singlet oxygen ( 1 O 2 )-dri...

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Literature Corpus work
2aa949a7-07ae-5dec-9294-d72f82b83808
DOI
10.64898/2026.02.22.707251
Open publication

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Clamp the LAMP: a photoelectrochemical platform for <i>KRAS</i> mutation detection via wild-type blockingDOI 10.64898/2026.02.22.707251
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