Article

Single cell DNA sequencing reveals distinct molecular types of basal cell carcinoma with unique transcriptome features

2018-12-11

Abstract excerpt

<h4>Background: </h4> Aneuploidy, a hallmark of cancer, is the result of chromosomal instability (CIN) during mitosis. While some aneuploid cancers display stable karyotypes, other tumours display cell-to-cell karyotype variability indicative of CIN. CIN cancers are typically associated with poor clinical outcome, as they are endowed with the potential to adjust their genomes to changing conditions including thera...

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Literature Corpus work: 2a822520-63d3-5b82-8755-778c9ec3c957
DOI: 10.1101/492199

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