Article

Heterogeneity of circulating epithelial cells in breast cancer at single-cell resolution: identifying tumor and hybrid cells

2021-11-25

Abstract excerpt

Circulating tumor cells and hybrid cells formed by the fusion of tumor cells with normal cells are leading players in metastasis and have prognostic relevance. Circulating tumor cells and hybrid cells are identified as CD45-negative and CD45-positive epithelial cells. However, such an approach is challenging because epithelial cells are observed in the blood of healthy individuals. In this study, we applied single...

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Literature Corpus work: 0b1f2f68-07bf-59ed-8900-5292a590fba6
DOI: 10.1101/2021.11.24.469962

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