Back to search

Article

Aberrant DNA Methylation in Cholangiocarcinoma

2017-05-16

Abstract excerpt

Cholangiocarcinoma is an epithelial malignancy arising in the region between the intrahepatic bile ducts and the ampulla of Vater at the distal end of the common bile duct. The effect of current chemotherapy regimens against cholangiocarcinoma is limited, and the prognosis of patients with cholangiocarcinoma is poor. Aberrant DNA methylation and histone modification induce silencing of tumor suppressor genes and c...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
2a772d1a-3221-59c4-b9dd-f7beb14c3894
DOI
10.20944/preprints201705.0127.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Aberrant DNA Methylation in CholangiocarcinomaDOI 10.20944/preprints201705.0127.v1
Aberrant DNA Methylation as a Biomarker and a Therapeutic Target of CholangiocarcinomaSemantic proximity
The roles of epigenetic regulation in cholangiocarcinogenesisSemantic proximity
Genetic and epigenetic changes associated with cholangiocarcinoma: From DNA methylation to microRNAsSemantic proximity
Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targetsSemantic proximity
Genetic, Epigenetic, and Microenvironmental Drivers of Cholangiocarcinoma.Semantic proximity
Epigenetic alterations associated with cholangiocarcinoma (Review)Semantic proximity
Role of Histone Deacetylases in Carcinogenesis: Potential Role in CholangiocarcinomaSemantic proximity
Comprehensive analysis of DNA methylation and gene expression profiles in cholangiocarcinomaSemantic proximity
M6A RNA methylation in biliary tract cancer: the function roles and potential therapeutic implicationsSemantic proximity
miR-373 Negatively Regulates Methyl-CpG-Binding Domain Protein 2 (MBD2) in Hilar CholangiocarcinomaSemantic proximity
Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinomaSemantic proximity
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.Semantic proximity
Select a neighboring publication to make it the new centre.