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Article

Epigenetic alterations associated with cholangiocarcinoma (Review)

6 Jul 2009

Abstract excerpt

Cholangiocarcinoma (CCA) is a highly lethal malignant tumor arising from the biliary tract epithelium. Chronic inflammatory conditions, including primary sclerosing cholangitis, liver fluke infestation, and hepatolithiasis, are considered risk factors, but the cause is still unknown in most cases. Recent advances in molecular pathogenesis have highlighted the importance of epigenetic alterations, including...

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PMID: 19578760
DOI: 10.3892/or_00000428

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