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Article

Role of Histone Deacetylases in Carcinogenesis: Potential Role in Cholangiocarcinoma

23 Mar 2020

Abstract excerpt

Cholangiocarcinoma (CCA) is a highly invasive and metastatic form of carcinoma with bleak prognosis due to limited therapies, frequent relapse, and chemotherapy resistance. There is an urgent need to identify the molecular regulators of CCA in order to develop novel therapeutics and advance diseases diagnosis. Many cellular proteins including histones may undergo a series of enzyme-mediated post-translational...

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Share to Epigenetics and DNA Methylation
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PMID: 32210140
DOI: 10.3390/cells9030780

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