Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinoma

3 Sept 2016

Abstract excerpt

Cholangiocarcinoma (CC) is a rare malignancy of the extrahepatic or intrahepatic biliary tract with an outstanding poor prognosis. Non-surgical therapeutic regimens result in minimally improved survival of CC patients. Global genomic analyses identified a few recurrently mutated genes, some of them in genes involved in epigenetic patterning. In a previous study, we demonstrated global DNA methylation changes in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27593557
DOI: 10.1080/15592294.2016.1227899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cadherin-6 is a putative tumor suppressor and target of epigenetically dysregulated miR-429 in cholangiocarcinomaPMID 27593557Read ↗

Aberrant DNA Methylation in CholangiocarcinomaSemantic proximity Read ↗

Global Alterations of DNA Methylation in Cholangiocarcinoma Target the Wnt Signaling PathwaySemantic proximity Read ↗

Epigenetic DNA hypermethylation in cholangiocarcinoma: potential roles in pathogenesis, diagnosis and identification of treatment targetsSemantic proximity Read ↗

Aberrant DNA Methylation as a Biomarker and a Therapeutic Target of CholangiocarcinomaSemantic proximity Read ↗

Comprehensive analysis of DNA methylation and gene expression profiles in cholangiocarcinomaSemantic proximity Read ↗

Genetic and epigenetic changes associated with cholangiocarcinoma: From DNA methylation to microRNAsSemantic proximity Read ↗

Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.Semantic proximity Read ↗

The roles of epigenetic regulation in cholangiocarcinogenesisSemantic proximity Read ↗

Genomic landscapes reveal post-transcriptional modifier disruption in cholangiocarcinomaSemantic proximity Read ↗

Aberrant DNA methylation at genes associated with a stem cell-like phenotype in cholangiocarcinoma tumors.Semantic proximity Read ↗

Novel target genes and a valid biomarker panel identified for cholangiocarcinomaSemantic proximity Read ↗

Whole-Genome DNA Methylation Profiling of Intrahepatic Cholangiocarcinoma Reveals Prognostic Subtypes with Distinct Biological Drivers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.