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Comprehensive analysis of DNA methylation and gene expression profiles in cholangiocarcinoma

1 Dec 2019

Abstract excerpt

BACKGROUND: The incidence of cholangiocarcinoma (CCA) has risen in recent years, and it has become a significant health burden worldwide. However, the mechanisms underlying tumorigenesis and progression of this disease remain largely unknown. An increasing number of studies have demonstrated crucial biological functions of epigenetic modifications, especially DNA methylation, in CCA. The present study aimed to...

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PMID: 31889904
DOI: 10.1186/s12935-019-1080-y

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