Article

Insights into the ligand-free structure of cyclic diguanosine monophosphate I riboswitch of <i>Vibrio cholerae</i> using molecular dynamics simulation

2019-12-11

Abstract excerpt

Riboswitches are key cis regulatory elements present at 5’ UTRs of mRNAs. They play a critical role in gene expression regulation at transcriptional and translational level by binding selectively to specific ligands followed by conformational changes. Ligands bind to the aptamer of riboswitches and their complex structures have been solved, but ligand-free riboswitches structures are not available which is importa...

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Literature Corpus work: 2a3eb6b4-5993-50f6-8eae-e7b71c976895
DOI: 10.1101/871194

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