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Article

Structural insights into recognition of c-di-AMP by the ydaO riboswitch.

Nature chemical biology - 1 Sept 2014

Gao Ang, Serganov Alexander

Abstract excerpt

Bacterial second messenger cyclic di-AMP (c-di-AMP) is implicated in signaling DNA damage and cell wall stress through interactions with several protein receptors and a widespread ydaO-type riboswitch. We report the crystal structures of c-di-AMP riboswitches from Thermoanaerobacter pseudethanolicus and Thermovirga lienii determined at ∼3.0-Å resolution. In both species, the RNA adopts an unforeseen...

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Identifiers

PMID: 25086507
DOI: 10.1038/nchembio.1607
PMCID: PMC4294798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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