Article
Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .
Biochemistry - 31 Aug 2010
Smith Kathryn D, Lipchock Sarah V, Livingston Alison L, Shanahan Carly A, Strobel Scott A
Abstract excerpt
The bacterial second messenger c-di-GMP is used in many species to control essential processes that allow the organism to adapt to its environment. The c-di-GMP riboswitch (GEMM) is an important downstream target in this signaling pathway and alters gene expression in response to changing concentrations of c-di-GMP. The riboswitch selectively recognizes its second messenger ligand primarily through contacts with...
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