Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Ligand Analogues that Control c-di-GMP Riboswitches

30 May 2012

Abstract excerpt

Riboswitches for the bacterial second messenger c-di-GMP control the expression of genes involved in numerous cellular processes such as virulence, competence, biofilm formation, and flagella synthesis. Therefore, the two known c-di-GMP riboswitch classes represent promising targets for developing novel modulators of bacterial physiology. Here, we examine the binding characteristics of circular and linear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Biochemical and Structural Characterization
Share to RNA and protein synthesis mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22646696
DOI: 10.1021/cb300138n

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Ligand Analogues that Control c-di-GMP RiboswitchesPMID 22646696Read ↗

Cyclic Diguanylate Regulates Virulence Factor Genes via Multiple Riboswitches in Clostridium difficileSemantic proximity Read ↗

Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch .Semantic proximity Read ↗

Cyclic diguanylate riboswitches control bacterial pathogenesis mechanismsSemantic proximity Read ↗

Structural insights into recognition of c-di-AMP by the ydaO riboswitch.Semantic proximity Read ↗

A minimalist biosensor: Quantitation of cyclic di-GMP using the conformational change of a riboswitch aptamer.Semantic proximity Read ↗

Quantitative input-output dynamics of a c-di-GMP signal-transduction cascade in <i>Vibrio cholerae</i>Semantic proximity Read ↗

Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial SpeciesSemantic proximity Read ↗

Insights into the ligand-free structure of cyclic diguanosine monophosphate I riboswitch of <i>Vibrio cholerae</i> using molecular dynamics simulationSemantic proximity Read ↗

The RNA Domain Vc1 Regulates Downstream Gene Expression in Response to Cyclic Diguanylate in Vibrio cholerae.Semantic proximity Read ↗

Nucleotide binding by the widespread high-affinity cyclic di-GMP receptor MshEN domain.Semantic proximity Read ↗

A Rationally Designed c-di-AMP Förster Resonance Energy Transfer Biosensor To Monitor Nucleotide Dynamics.Semantic proximity Read ↗

Inactivation of the riboswitch-controlled GMP synthase GuaA in Clostridioides difficile is associated with severe growth defects and poor infectivity in a mouse model of infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.