Article

Input-and cell-type-specific developmental alterations to thalamic synapses in a Dravet syndrome mouse model

2026-02-13

Abstract excerpt

<h4>ABSTRACT</h4> Dravet syndrome is an epileptic encephalopathy most often caused by loss-of-function mutations in the SCN1A gene, leading to haploinsufficiency of the voltage-gated sodium channel Na V 1.1. Seizures begin during infancy and generally wane throughout childhood, but behavioral symptoms, such as intellectual disability, motor impairments, and autistic features, remain through adulthood. Seizures...

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Literature Corpus work: 2a2585d6-92b8-5b4c-baa5-cfbf82834c6e
DOI: 10.64898/2026.02.12.705567

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