Article

A Novel Method to Disentangle Tightly Linked Risk and Resilience Genes for Brain Disorders: Application to Alzheimer’s Disease

2025-02-27

Abstract excerpt

Genetic risk factors for neuropsychiatric disorders are well documented. However, some individuals with high genetic risk remain unaffected, and the mechanisms underlying such resilience remain poorly understood. The presence of protective resilience factors that mitigate risk could help explain the disconnect between predicted risk and reality, particularly when genetic contributions are substantial but incomplet...

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Literature Corpus work: 29dbc7f2-e3bf-5252-a143-d80f2d9ccf06
DOI: 10.1101/2025.02.26.25322962

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