Article

Secretion and signaling properties of Wnt11 and Wnt3 are determined by their N-terminus

2025-07-02

Abstract excerpt

<h4>ABSTRACT</h4> Wnt proteins are evolutionarily conserved signaling molecules that control cell-cell communication in health and disease. While different Wnt proteins share a requirement for palmitoleoylation and the cargo receptor Evi/Wls for their secretion, they interact with diverse signaling receptors and co-receptors to elicit distinct outcomes in signal-receiving cells. The molecular mechanisms underlyin...

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Literature Corpus work: 297aceb3-4155-5b64-8dd7-a83cd77f8f8f
DOI: 10.1101/2025.07.02.662750

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