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Article

Secretion of Wnt ligands requires Evi, a conserved transmembrane protein.

Cell - 5 May 2006

Bartscherer Kerstin, Pelte Nadège, Ingelfinger Dierk, Boutros Michael

Abstract excerpt

Wnt signaling pathways are important for multiple biological processes during development and disease. Wnt proteins are secreted factors that activate target-gene expression in both a short- and long-range manner. Currently, little is known about how Wnts are released from cells and which factors facilitate their secretion. Here, we identify a conserved multipass transmembrane protein, Evenness interrupted...

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Identifiers

PMID: 16678096
DOI: 10.1016/j.cell.2006.04.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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