Article
Dynamic association with donor cell filopodia and lipid-modification are essential features of Wnt8a during patterning of the zebrafish neuroectoderm.
PloS one - 1 Jan 2014
Luz Marta, Spannl-Müller Stephanie, Özhan Günes, Kagermeier-Schenk Birgit, Rhinn Muriel, Weidinger Gilbert, Brand Michael
Abstract excerpt
BACKGROUND: Wnt proteins are conserved signaling molecules that regulate pattern formation during animal development. Many Wnt proteins are post-translationally modified by addition of lipid adducts. Wnt8a provides a crucial signal for patterning the anteroposterior axis of the developing neural plate in vertebrates. However, it is not clear how this protein propagates from its source, the blastoderm margin, to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
