Article

<i>In vitro</i> dormancy models improve ability to predict treatment response in severe marmoset tuberculosis lesions

2026-05-15

Abstract excerpt

Tuberculosis lesions are structurally and physiologically heterogeneous, creating microenvironments that restrict antibiotic penetration and alter bacterial susceptibility. This heterogeneity remains a major impediment to shortening tuberculosis treatment, as it is difficult to predict which regimens will sterilize bacteria in these hard-to-treat lesion niches. Many in vitro systems and commonly used animal model...

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Literature Corpus work: 28ed1193-acbd-5feb-9689-3a0bd3db996b
DOI: 10.64898/2026.05.13.724664

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