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Article

Eradication of Drug-Tolerant Mycobacterium tuberculosis 2022: Where We Stand

2023-04-29

Abstract excerpt

The lungs of tuberculosis (TB) patients contain a spectrum of granulomatous lesions ranging from solid and well vascularized cellular granulomas, to avascular caseous granulomas. In solid granulomas, current therapy kills actively replicating (AR) intracellular bacilli, while in low vascularized caseous granulomas the low oxygen tension stimulates aerobic and microaerophilic AR bacilli to transit into non-replicat...

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Literature Corpus work
a01687a5-7345-569b-842a-a20f8e60c89e
DOI
10.20944/preprints202304.1233.v1
Open publication

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