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Methodology for a freshly engineered or cryo-preserved 3D tuberculoma bioplatform for studying tuberculosis biology and high-content screening of therapeutics

2025-08-31

Abstract excerpt

Tuberculomas are the conglomeration of tuberculous granulomas into structurally organized three-dimensional (3D) masses that result from Mycobacterium tuberculosis infection and represent one of the more severe morphological forms of tuberculosis (TB). Several in vitro models that mimic human TB granulomas have been reported to decipher complex host-pathogen interactions and discover new prophylactic and therape...

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Identifiers and source

Literature Corpus work
e9cd6a42-2228-5114-a245-e69123c483c8
DOI
10.1101/2025.08.27.672606
Open publication

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Methodology for a freshly engineered or cryo-preserved 3D tuberculoma bioplatform for studying tuberculosis biology and high-content screening of therapeuticsDOI 10.1101/2025.08.27.672606
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