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Distinguishing multiple roles of T cell and macrophage involvement in determining lymph node fates during Mycobacterium tuberculosis infection

7 May 2025

Abstract excerpt

Tuberculosis (TB) is a disease of major public health concern with an estimated one-fourth of the world currently infected with M. tuberculosis (Mtb) bacilli. Mtb infection occurs after inhalation of Mtb, following which, highly structured immune structures called granulomas form within lungs to immunologically restrain and physically constrain spread of infection. Most lung granulomas are successful at...

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PMID: 40334195
DOI: 10.1371/journal.pcbi.1013033

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