Article

Identification and characterization of host-directed therapeutics for tuberculosis using a versatile human 3D tuberculoma bioplatform

2025-09-01

Abstract excerpt

Host-directed therapies (HDT) represent a pivotal strategy in combating both drug-susceptible and drug-resistant tuberculosis (TB). Current evaluations, however, show limited success in animal models and clinical settings, emphasizing the need for more effective HDT candidates. With few druggable targets validated within granulomas, it is essential to verify the effectiveness of HDT candidates identified through t...

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Literature Corpus work: aa564bb5-951b-5a8e-814e-415dfe9020b1
DOI: 10.1101/2025.08.27.672670

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