Article

Inferring the immune response from repertoire sequencing

2019-12-18

Abstract excerpt

High-throughput sequencing of B- and T-cell receptors makes it possible to track immune repertoires across time, in different tissues, and in acute and chronic diseases or in healthy individuals. However, quantitative comparison between repertoires is confounded by variability in the read count of each receptor clonotype due to sampling, library preparation, and expression noise. Here, we present a general Bayesia...

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Literature Corpus work: db6ac836-afa9-5f3c-8e04-52b9699f94be
DOI: 10.1101/2019.12.17.880138

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