Article

Vaccination reshapes the virus-specific T cell repertoire in unexposed adults

2020-10-06

Abstract excerpt

How baseline T cell characteristics impact human T cell responses to novel pathogens remains unknown. Here, we address this question by studying the CD4+ T cell response in unexposed individuals to live attenuated yellow fever virus (YFV) vaccine. We quantified virus-specific population dynamics over time using class II peptide-MHC tetramers. Our data revealed that, even in the absence of known viral exposure, mem...

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Literature Corpus work: a6f6cac8-e2fe-574e-9deb-2ee3a9b36393
DOI: 10.1101/2020.10.01.322958

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