Article

Genome instability footprint under rapamycin and hydroxyurea treatments

2023-03-01

Abstract excerpt

<h4>Summary</h4> The mutational processes dictating the accumulation of mutations in genomes are shaped by genetic background, environment and their interactions. Accurate quantification of mutation rates and spectra under drugs has important implications in disease treatment. Here, we used whole-genome sequencing and time-resolved growth phenotyping of yeast mutation accumulation lines to give a detailed view of...

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Literature Corpus work: 287e0658-1930-5dc7-a0c0-fc407a9a9743
DOI: 10.1101/2023.02.28.530484

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