Article

Live imaging and biophysical modeling support a button-based mechanism of somatic homolog pairing in <i>Drosophila</i>

2020-08-31

Abstract excerpt

The spatial configuration of the eukaryotic genome is organized and dynamic, providing the structural basis for regulated gene expression in living cells. In Drosophila melanogaster , 3D genome organization is characterized by somatic homolog pairing, where homologous chromosomes are intimately paired from end to end; however, the process by which homologs identify one another and pair has remained mysterious. A...

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Literature Corpus work: 2817029c-95bb-508a-a361-98190706d58d
DOI: 10.1101/2020.08.30.265108

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