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Characterization of genomic variants associated with resistance to bedaquiline and delamanid in naïve <i>Mycobacterium tuberculosis</i> clinical strains

2020-05-29

Abstract excerpt

The role of genetic mutations in genes associated to phenotypic resistance to bedaquiline (BDQ) and delamanid (DLM) in Mycobacterium tuberculosis complex (MTBc) strains is poorly understood. However, a clear understanding of the role of each genetic variant is crucial to guide the development of molecular-based drug susceptibility testing (DST). In this work, we analysed all mutations in candidate genomic regions...

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Literature Corpus work
27bbd9b0-33cd-5779-99ec-8507ccb1bac3
DOI
10.1101/2020.05.27.120451
Open publication

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Characterization of genomic variants associated with resistance to bedaquiline and delamanid in naïve <i>Mycobacterium tuberculosis</i> clinical strainsDOI 10.1101/2020.05.27.120451
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