Article

Key features of the innate immune response is mediated by the immunoproteasome in microglia

2024-06-06

Abstract excerpt

<title>Abstract</title> <p>Microglia are the resident immune cells of the central nervous system (CNS). We and others have shown that the inflammatory response of microglia is partially regulated by the immunoproteasome, an inducible form of the proteasome responsible for the generation of major histocompatibility complex (MHC) class I epitopes. While the role of the proteasome in the adaptive immune system is we...

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Literature Corpus work: 26e2e40b-ea40-5add-8fbd-f14f2ac68f97
DOI: 10.21203/rs.3.rs-4467983/v1

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