Article

TNFAIP3 in circulating and parenchymal myeloid lineage critically controls monocytes, monocytes-derived cells and microglia

2019-12-03

Abstract excerpt

<title>Abstract</title> <p><bold>Background.</bold> The intracellular ubiquitin-ending enzyme TNFAIP3 is one of the most potent inhibitor of the pro-inflammatory NF-kB pathway. Single nucleotide polymorphisms in the TNFAIP3 locus have been associated to autoimmune inflammatory disorders, including Multiple Sclerosis (MS). Previously, we reported a TNFAIP3 down-regulated gene expression level in blood and specific...

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Literature Corpus work: 1ffd8c9f-c32c-5155-ae74-cf7910c9316d
DOI: 10.21203/rs.2.17968/v1

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