Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inflammasomes in neurological diseases: emerging pathogenic and therapeutic concepts

19 May 2017

Abstract excerpt

Inflammasome activation in the central nervous system occurs in both health and disease. Inflammasomes are cytosolic protein complexes that sense specific infectious or host stimuli and initiate inflammatory responses through caspase activation. Assembly of inflammasomes results in caspase-1-mediated proteolytic cleavage and release of the pro-inflammatory cytokines, interleukin-1β and interleukin-18, with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Inflammasome and immune disorders
Share to Kawasaki Disease and Coronary Complications
Share to Tryptophan and brain disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29050380
DOI: 10.1093/brain/awx133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inflammasomes in neurological diseases: emerging pathogenic and therapeutic conceptsPMID 29050380Read ↗

Inflammasomes and Their Roles in Health and DiseaseSemantic proximity Read ↗

Inflammasome activation and assembly at a glanceSemantic proximity Read ↗

Deregulated inflammasome signaling in disease.Semantic proximity Read ↗

Sensing pathogens and danger signals by the inflammasome.Semantic proximity Read ↗

Targeting the NLRP3 inflammasome in chronic inflammatory diseases: current perspectivesSemantic proximity Read ↗

Inflammasomes: mechanism of action, role in disease, and therapeuticsSemantic proximity Read ↗

The cell biology of inflammasomes: Mechanisms of inflammasome activation and regulationSemantic proximity Read ↗

Regulation of inflammasome activation.Semantic proximity Read ↗

Inflammasome-mediated autoinflammatory disorders.Semantic proximity Read ↗

The inflammasome in pathogen recognition and inflammationSemantic proximity Read ↗

Emerging insights into molecular mechanisms underlying pyroptosis and functions of inflammasomes in diseasesSemantic proximity Read ↗

Toward targeting inflammasomes: insights into their regulation and activationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.