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Changes in social behaviour with alterations of MAPK3 and KCTD13/CUL3 pathways in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disorders

2023-02-11

Abstract excerpt

<h4>ABSTRACT</h4> Copy number variations (CNVs) of the human 16p11.2 locus are associated with several developmental/neurocognitive syndromes. Particularly, deletion and duplication of this genetic interval are found in patients with autism spectrum disorders, intellectual disability and other psychiatric traits. The high gene density associated with the region and the strong phenotypic variability of incomplete...

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Literature Corpus work
26c5164d-38aa-59a5-af58-f2c2525591c6
DOI
10.1101/2023.02.11.528123
Open publication

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Changes in social behaviour with alterations of MAPK3 and KCTD13/CUL3 pathways in two new outbred rat models for the 16p11.2 syndromes with autism spectrum disordersDOI 10.1101/2023.02.11.528123
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