Article

Two Novel Mouse Models Mimicking Minor Deletions in 22q11.2 Deletion Syndrome Revealed the Contribution of Each Deleted Region to Psychiatric Disorders

2020-12-31

Abstract excerpt

<title>Abstract</title> 22q11.2 deletion syndrome (22q11.2DS) is a disorder caused by the segmental deletion of human chromosome 22. This chromosomal deletion is known as high genetic risk factors for various psychiatric disorders. The different deletion types are identified in 22q11.2DS patients, including the most common 3.0-Mb deletion, and the less-frequent 1.5-Mb and 1.4-Mb deletions. In previous animal s...

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Literature Corpus work: 3cfc0692-da76-5d27-a594-deef12d18201
DOI: 10.21203/rs.3.rs-137341/v1

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