Article

Genome-wide association study of open field behavior in outbred heterogeneous stock rats identifies multiple loci implicated in psychiatric disorders

2021-10-19

Abstract excerpt

Many personality traits are influenced by genetic factors. Rodents models provide an efficient system for analyzing genetic contribution to these traits. Using 1,246 adolescent heterogeneous stock (HS) male and female rats, we conducted a genome-wide association study (GWAS) of behaviors measured in an open field, including locomotion, novel object interaction, and social interaction. We identified 30 genome-wide...

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Literature Corpus work: c8ddca72-4ed7-5449-a032-baad9dd159b7
DOI: 10.1101/2021.10.18.464872

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