Article

Day-to-day spontaneous social behaviours is quantitatively and qualitatively affected in a 16p11.2 deletion mouse model

2022-09-16

Abstract excerpt

<h4>Background</h4> Autism spectrum disorders affect more than one percent of the population, impairing social communication and increasing stereotyped behaviours. A micro-deletion of the 16p11.2 BP4-BP5 chromosomic region has been identified in one percent of patients also displaying intellectual disabilities. In mouse models generated to understand the mechanisms of this deletion, learning and memory deficits w...

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Literature Corpus work: 6faa10ff-d19d-578e-9738-a43980957f35
DOI: 10.1101/2022.09.16.508234

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